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Therefore, Tc17 can induce the expression of IL-6 and IL-8 by synovial fibroblasts and can be inhibited by anti-TNF-α and anti-IL-17A agent (64)
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Research in animal models has documented increased longitudinal bone growth in young subjects (PMID: 10373343) and increased bone mineral content (BMC) due to increased volume of bone, though bone mineral density itself remained unchanged (PMID: 10828840)
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