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Importantly, this IL-17-induced STEAP4-dependent cellular copper uptake is critical for colon tumor formation in a murine model of colitis-associated tumorigenesis and STEAP4 expression correlates with IL-17 level and XIAP activation in human colon cancer
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Toxic Mechanisms The underlying mechanisms of As-induced neurotoxicity mostly remain unknown, though several mechanisms have been proposed, mainly from animal experiments
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