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High iron loads diminish responsiveness to interferon-gamma (IFN-γ), resulting in reduced expression of anti-inflammatory factors like TNF-α and MHC class II antigens, leading to Th1/Th2 imbalance with weakened Th1 effector functions and increased production of Th2-mediated cytokines
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Investigation of the role of extracellular H2O2 and transition metal ions in the genotoxic action of ascorbic acid in cell culture models
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